A transplant center designated as a Comprehensive Report Form center will submit data on the Pre-TED (2400) and Disease Classification (2402) Forms, followed by either the Post-TED (2450) Form or the Comprehensive Report Forms. The type of follow-up forms required for a specific recipient is determined by the CIBMTR’s form selection algorithm.
The Post-Infusion Form (2100) must be completed at the following time points: 100 days, 6 months, annually for 6 years post-HCT, and biennially thereafter. This form should be completed as closely to these time points as possible. The following recipient data should be collected from an actual examination (or other recipient contact) by the transplant center physician or the local physician who is following the recipient post-HCT: vital status, hematopoietic reconstitution post-HCT, neutrophil recovery, platelet recovery, current hematologic findings, immune reconstitution, chimerism studies, engraftment syndrome, acute Graft-versus-Host Disease (GVHD), chronic GVHD, infections, organ function, new malignancy, functional status, and subsequent HCT.
Subsequent Infusions
If a recipient receives a subsequent HCT between time points (100 day, 6 months, annually), the CRF form sequence will start over again with another Pre-TED.
However, if the recipient receives an autologous HCT as a result of a poor graft or graft failure or an allogeneic infusion using a prior donor for poor graft function / insufficient donor chimerism, the CRF form sequence will not start over again. Generally, this type of infusion (autologous rescue and allogeneic boosts) are used to treat the recipient’s poor graft response, rather than to treat the recipient’s disease. The Indication for CIBMTR Data Reporting (2814) will come due for both autologous rescues and allogeneic boosts; however, after completing the form, the Donor Cellular Infusion (2199) will only come due for allogeneic boosts.
Contact CIBMTR Center Support if the subsequent Pre-TED does not come due automatically.
Lost to Follow Up
Occasionally, centers may lose contact with recipients for a variety of reasons, including the recipient moving, changing physicians, or death. If contact with a recipient appears lost, please consider calling the recipient at home or work, sending a letter, communicating with the treating or referring physician, or contacting the hospital billing department. If no documentation exists and several unsuccessful attempts have been made to contact the recipient, they are considered lost to follow-up and the form may be marked as such using the Lost to Follow-Up Tool in FormsNet3 for each reporting period in which no contact exists.
Links to Sections of Form
Q1 – 3: Vital Status
Q4 – 10: Granulopoiesis / Neutrophil Recovery
Q11 – 14: Megakaryopoiesis / Platelet Recovery
Q15 – 23: Growth Factor and Cytokine Therapy
Q24 – 33: Current Hematologic Findings
Q34 – 49: Immune Reconstitution
Q50: Gene Therapy Persistence Testing
Q51: Chimerism Studies
Q52 – 62: Engraftment Syndrome
Q63 – 111: Acute Graft vs. Host Disease
Q112 – 181: Chronic Graft vs. Host Disease
Q182 – 188: Current GVHD Status
Q189 – 204: Infection Prophylaxis
Q205 – 221: Infection
Q222: New Malignancy, Lymphoproliferative or Myeloproliferative Disease / Disorder
Q223 – 247: Functional Status
Manual Updates
Sections of the Forms Instruction Manual are frequently updated. The most recent updates to the manual can be found below. For additional information, select the manual section and review the updated text.
If you need to reference the historical Manual Change History for this form, please review the table below or reference the retired manual section on the Retired Forms Manuals webpage.
| Date | Manual Section | Add/Remove/Modify | Description |
|---|---|---|---|
| 3/27/2026 | 2100:Post-Infusion Follow-Up Form | Modify | Version 10 of the 2100: Post-Infusion Follow-Up section of the Forms Instructions Manual released. Version 10 corresponds to revision 10 of the Form 2100 |
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