Complete Remission (CR)
Normalization of WBC and resolution of organomegaly.
Partial Remission (PR)
≥ 50% reduction of WBC from maximum pre-treatment value and/or ≥ 50% reduction of organomegaly from pre-treatment maximum
Marginal Response (MR)
25-50% reduction of WBC from maximum pre-treatment value and 25-50% reduction of organomegaly from pre-treatment maximum
or
≥ 50% reduction of WBC from maximum pre-treatment value and no change in organomegaly
or
≥ 50% reduction of organomegaly from pre-treatment maximum and no change in WBC
Stable Disease (SD)
≤ 25% reduction of WBC from maximum pre-treatment value and/or ≤ 25% reduction of organomegaly from pre-treatment maximum
Progressive Disease (PD)
Increase in WBC and/or organomegaly
Relapse
Reappearance of disease characteristics such as leukocytosis, absolute monocytosis, and organomegaly after complete remission (CR)
Not assessed
No assessment of leukocytosis or organomegaly was done at any time after therapy. If the patient was not treated, no assessment of leukocytosis or organomegaly was done at any time after diagnosis.
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