2006: Hematopoietic Stem Cell Transplant (HCT) Infusion

Centers must complete the Hematopoietic Cellular Transplant (HCT) (2006) for each product when the recipient is assigned to the Comprehensive Report Form track. Centers must also complete the Hematopoietic Cellular Transplant (HCT) (2006) for the following product types when the recipient is assigned to the TED track:

• NMDP donor products
• NMDP and non-NMDP cord blood units
• Any product co-infused with a cord blood unit

Additionally, all transplant centers (TED-only and Comprehensive Report Form) participating in the Related Sample Repository must complete the Hematopoietic Cellular Transplant (HCT) (2006) for all non-NMDP donor products when a research sample is collected.

The Hematopoietic Cellular Transplant (HCT) (2006) is designed to capture product- and infusion-specific information for all products given to a recipient as part of a Hematopoietic Stem Cell Transplant (HCT). This includes cells given prior to the HCT for reasons other than engraftment. In addition to use in research, this information is used for quality assurance measures, both by the NMDP and the Cord Blood Banks.

Multiple Products Infused

If more than one type of product is infused, FormsNet3^SM will determine if multiple Hematopoietic Cellular Transplant (HCT) (2006) forms are required to report separate product information and analyses. When several products are infused, multiple Hematopoietic Cellular Transplant (HCT) (2006) forms may be required but only if each product meets the criteria for form submission.
In some cases, multiple products infused will each meet the requirements, resulting in multiple Hematopoietic Cellular Transplant (HCT) (2006) forms coming due. In other instances, only one product may meet the requirement and therefore, only a single Hematopoietic Cellular Transplant (HCT) (2006) form will come due.

When only one form comes due after multiple products are infused, the donor’s information for the qualifying product will auto-populate on the form. That form will only capture data relevant to that specific product. Do not combine and / or report the results for multiple products on a single form.

Examples of more than one product infused includes, but are not limited to:

• Two different products from the same donor (i.e., PBSC and bone marrow)
• A co-infusion of two products (i.e., haplo donor PBSC and CBU)
  

Requirements for making the Hematopoietic Cellular Transplant (HCT) (2006) come due, based by product type, is found in the How Forms Come Due section of the Data CIBMTR Data Management Guide .

Additionally, a series of collections from the same donor that uses the same collection method and mobilization cycle, even if the collections are performed on different days, should be considered a single product.

For more information see Appendix D: How to Distinguish Infusion Types and Appendix E: Definition of a Product.

Links to Sections of Form:
Q1 – 3: Pre-Collection Therapy
Q4 – 7: Product Collection
Q8 – 21: Product Transport and Receipt
Q22 – 41: Product Processing / Manipulation
Q42 – 83: Product Analysis at Infusion
Q84 – 133: Product Infusion
Q134 – 159: Donor / Infant Demographic Information

Manual Updates:
Sections of the Forms Instruction Manual are frequently updated. The most recent updates to the manual can be found below. For additional information, select the manual section and review the updated text.

To reference the historical Manual Change History for this form, review the Retired Forms Manuals webpage.

Date	Manual Section	Add/Remove/Modify	Description
7/24/2026	2006: Hematopoietic Stem Cell Transplant (HCT) Infusion	Add	Clarified how to report Q85 when product is processed / manipulated: Indicate if the entire product volume received (all bags or all compartments) by the center was infused. The product volume received refers to the product intended for infusion after any processing or manipulation has been completed. Do not include portions of the product that were removed during processing or manipulation (e.g., plasma reduction, RBC reduction, T-cell depletion, or other cell separation methods). See the examples below for further clarification. Example 1: A PBSC product was collected and arrived at the center in four bags. Two of the bags are infused fresh, and the remaining two bags are cryopreserved for future use. Since a portion of the product received was not infused, report No the entire volume of the product received by the center was not infused. Example 2: A bone marrow product was collected and arrived at the center in two bags and both bags of the fresh product are infused. As the entire volume of the received product was infused report Yes, the entire volume of the product received by the center was infused. Example 3: A PBSC product was collected and arrived at the center in two bags. Both bags were cryopreserved and only one bag was thawed and infused, with the remaining bag still cryopreserved for future use. Since a portion of the product received was not infused, report No, the entire volume of the product received by the center was not infused. Example 4: A bone marrow product was collected and arrived at the center. The product was RBC and plasma reduced, with the remaining product contained in two bags, and both bags were infused. As the entire remaining volume of the received product was infused, report Yes, the entire volume of the product received by the center was infused.
7/24/2026	2006: Hematopoietic Stem Cell Transplant (HCT) Infusion	Add	Clarified how to answer Q86 when the product is processed / manipulated: Report on what happened to the reserved portion of the product. Select all that apply. Only report on portions of the product intended for infusion that were not infused after receipt at the center. Do not report for portions of the product that were removed during product processing or manipulation. If Other fate is selected, report the outcome of this product.
10/24/2025	2006: Hematopoietic Stem Cell Transplant (HCT) Infusion	Modify	Version 6 of the 2006: Hematopoietic Stem Cell Transplant (HCT) Infusion section of the Forms Instruction Manual released. Version 6 corresponds to revision 7 of the Form 2006.

Copyright © 2004-2026 The Medical College of Wisconsin, Inc. and NMDP. All Rights Reserved.
CIBMTR® (Center for International Blood and Marrow Transplant Research) is a research collaboration between the Medical College of Wisconsin and NMDP.