Q26 – 31: Treatment of Infection

Question 26: Did the recipient receive any therapy between 7 days prior to the date of infection diagnosis and the date of infusion?

Specify if any antifungal drugs were given between seven days prior to the infection diagnosis date and the infusion date (i.e., Day 0 of the HCT or cellular therapy).

If the dose of fungal prophylaxis increased between seven days prior to the infection diagnosis date and the infusion date, select Yes.

If antifungal drugs were not given between seven days prior to the infection diagnosis date and the infusion date, or it is unknown if given, select No.

*Reporting Multiple Antifungal Drugs
Complete Antifungal drugs through Date started questions to report all antifungal drugs given between seven days prior to the diagnosis date and the infusion date by adding an additional instance in the FormsNet3^SM application.

Questions 27 – 30: Antifungal drugs

Specify the antifungal drug given seven days prior to the infection diagnosis date and the infusion date and the therapy start date. If an antifungal drug was given but not listed, select Other antifungal drug and specify.

If an antifungal drug was started greater than seven days prior to the date of infection diagnosis and continued within seven days of the diagnosis date, report the therapy start date as seven days prior to the infection diagnosis.

If the exact start date is not known, use the guidelines for reporting estimated dates in General Instructions, General Guidelines for Completing Forms.

!Infection Status
The Unknown option should never be used to report the status of the infection. The options on the form will be revised with next revision of this form.

Question 31: What was the status of the infection? (at the last evaluation prior to the start of the preparative regimen)

Report the status of the fungal infection immediately prior to the start of the preparative regimen / lymphodepleting therapy (or infusion if no preparative regimen / lymphodepleting therapy was given) based on the primary care provider’s clinical judgement.

If the status of the infection is not documented prior to the start of the preparative regimen / lymphodepleting therapy, seek clinician clarification.

Select Ongoing if the infection is still present but cannot be considered improved or resolved.

Section Updates:

Question Number	Date of Change	Add/Remove/Modify	Description	Reasoning (If applicable)
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