Question 69: Was proteinuria detected? (excluding microalbuminuria)
Proteinuria, also known as albuminuria, is excess protein in the urine and may be a sign of kidney disease. Proteinuria may be assessed by 24-hour urine collection or by a dipstick analysis. A value of > 150 mg by 24-hour urine collection or ‘positive’ by a dipstick analysis is indicative of proteinuria.
Indicate if proteinuria was detected (excluding microalbuminuria) in the current reporting period. Report Yes if the proteinuria was:
• > 150 mg by 24-hour urine collection or
• ‘Positive’ or trace, 1+, 2+, 3+, or 4+ result by urine dipstick analysis.
Report No if the proteinuria was:
• ≤ 150 mg (by 24-hour urine collection) or
• ‘Negative’ result (by urine dipstick analysis)
If proteinuria was assessed multiple times during the reporting period, report based on the results of the most recent assessment.
If proteinuria was not assessed during the current reporting period, select Not done.
Questions 70 – 71: Serum creatinine
Creatinine is a normal metabolic waste that is primarily filtered from the blood by the kidneys and then excreted in the urine. Since it is generally produced at a constant rate, the clearance rate and the serum level are widely used as indicators of kidney function.
Indicate if the serum creatinine is known. If Known, report the most recent serum creatinine value available in the current reporting period and specify the units of measurement.
Questions 72-73: Glomerular Filtration Rate (GFR)
The glomerular filtration rate (GFR) estimates how much blood passes through the glomeruli each minute and is used to check how well the kidneys are working. Indicate whether the GFR was measured prior to the start of the preparative regimen / infusion. If measured, select Known and report the laboratory value and unit of measure documented on the laboratory report. If testing was performed multiple times, report the most recent laboratory value obtained. If the GFR was not measured or if no information is available to determine if the GFR was assessed, report Unknown.
GFR may be reported to the CIBMTR as “actual” or “calculated.” If your center’s laboratory does not calculate the actual GFR value, use the Cockcroft-Gault equation (see equation below) to determine the calculated value.
Cockcroft-Gault Equation
GFR = ((140-age)x Wt)/(72 x Cr)
- GFR_cg = Glomerular Filtration Rate (Cockcroft) (mL / min)
- Age = Patient Age (years)
- Sex = Gender (Male)
- If female, multiply result by 0.85
- Wt = Body Weight (kg)
- Cr = Creatinine (S, mg / dL)
If the laboratory report indicates the GFR as a range, report the average. Example, if the laboratory report indicates GFR is 80 – 120, report “100.”
For values expressed as g “> X,” report the value as “X+1.” Example, if the laboratory report indicates the GFR is greater than 120, report “121.”
If the laboratory report indicates the GFR “< X,” report the value as “X-1.” Example, if f the GFR is reported as < 80, report “79.”
Section Updates:
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