Q1 – 2: Geographic Ancestry

*Race, Ethnicity, and Ancestry (REA) Forms Updates
As part of the Fall 2025 Quarterly Release, ethnicity and race data fields were expanded to add geographic ancestry. On the Pre-TED (2400) and Cellular Therapy Essential Data Pre-Infusion (4000) forms, the Ethnicity and Race data fields will be disabled. The expanded REA details are only collected on the Race, Ethnicity and Ancestry (2807) Form. Review Appendix I: Race, Ethnicity and Ancestry for additional details.

An individual’s ancestral background, determined by where generations of their ancestors came from, shapes their genetic composition. How an individual identifies their race, ethnicity, and ancestry helps to understand their genetic composition and is used in transplant clinical research and operations. Collecting more detailed race, ethnicity, and ancestry data provides better access to transplants and cellular therapies, helps to identify the need for more refined patient populations, and supports future research.

With the Fall 2025 Quarterly Release, CIBMTR approved an expanded race, ethnicity and ancestry list. Refer to Appendix I: Race, Ethnicity and Ancestry for information on the reasons for these changes.

*Self-Reported REA Data
When possible, use the recipient’s self-reported REA data instead of REA data obtained through other methods. Refer to the articles provided on the Data Management Guide for more information.

Question 1: Geographic ancestry (select one or more options that closest identifies the patient’s background)

Report the recipient’s geographic ancestry. Check all options that apply.

Select Not otherwise specified in the following scenarios:

• The race, ethnicity or ancestry is unknown.
• The race, ethnicity or ancestry is not documented.
• The race, ethnicity or ancestry is known but does not fit one of the options available on the form (i.e., the source documentation specifically notes the patient’s race, ethnicity, and / or ancestry as ‘other,’ ‘two or more races’ (but documentation does not specifically state the races), etc.).
  

Select Prefer not to answer in the following scenarios:

• If the recipient declines to provide their geographic ancestry.
• If the recipient is not a US resident and the country’s rules / regulations prohibit the collection or reporting of race, ethnicity or ancestry.
  

Review Appendix I: Race, Ethnicity and Ancestry for more information on the geographic ancestry response options.

Question 2: Geographic ancestry detail (select one or more options that closest identifies the patient’s background)

Report the recipient’s geographic ancestry detail. Check all options that apply. Review Appendix I: Race, Ethnicity and Ancestry for guidance on when to use the ‘other’ or ‘not otherwise specified’ option.

Section Updates:

Question Number	Date of Change	Add/Remove/Modify	Description	Reasoning (If applicable)
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CIBMTR® (Center for International Blood and Marrow Transplant Research) is a research collaboration between the Medical College of Wisconsin and NMDP.